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Original Article
- Factors associated with in-hospital death in patients with nosocomial infections: a registry-based study using community data in western Iran
- Salman Khazaei, Erfan Ayubi, Ensiyeh Jenabi, Saeid Bashirian, Masud Shojaeian, Leili Tapak
- Epidemiol Health. 2020;42:e2020037. Published online June 1, 2020
- DOI: https://doi.org/10.4178/epih.e2020037
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- 2 Web of Science
- 6 Crossref
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AbstractObjectives
Determining the predictors of in-hospital death related to nosocomial infections is an essential part of efforts made in the overall health system to improve the delivery of health care to patients. Therefore, this study investigated the predictors of in-hospital death related to nosocomial infections.MethodsThis registry-based, longitudinal study analyzed data on 8,895 hospital-acquired infections (HAIs) in Hamadan Province, Iran from March 2017 to December 2019. The medical records of all patients who had been admitted to the hospitals were extracted from the Iranian Nosocomial Infections Surveillance Software. The effects of the type and site of infection, as well as age group, on in-hospital death were estimated using univariate and multivariable Cox regression models.ResultsIn total, 4,232 (47.8%) patients with HAIs were males, and their mean age was 48.25±26.22 years. In both sexes, most nosocomial infections involved Gram-negative bacteria and the most common site of infection was the urinary tract. Older patients had a higher risk of in-hospital death (adjusted hazard ratio [aHR], 2.26; 95% confidence interval [CI], 1.38 to 3.69 for males; aHR, 2.44; 95% CI, 1.29 to 4.62 for females). In both sexes, compared with urinary tract infections, an increased risk of in-hospital death was found for ventilator-associated events (VAEs) (by 95% for males and 93% for females) and bloodstream infections (BSIs) (by 67% for males and 82% for females).ConclusionWe found that VAEs, BSIs, and fungal infections were independently and strongly associated with increased mortality. -
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Fereshteh Rezaie, Farahnaz Mohammadi-Shahboulaghi, Reza Fadayevatan, Mohsen Shati, Gholamreza Ghaedamini Harouni
Journal of Kermanshah University of Medical Sciences.2023;[Epub] CrossRef - Barriers to hand hygiene compliance in intensive care units to prevent the spread of healthcare-associated infections
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Canadian Journal of Infectious Diseases and Medical Microbiology.2021; 2021: 1. CrossRef - Survival rate in patients with ICU-acquired infections and its related factors in Iran’s hospitals
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BMC Public Health.2021;[Epub] CrossRef
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